Publications and Outputs

2023

Hatam S, Scully ST, Cook S, Evans HT, Hume A, Kallis C, Farr I, Orton C, Sheikh A, Quint JK. A Harmonised Approach to Curating Research-Ready Datasets for Asthma, Chronic Obstructive Pulmonary Disease (COPD) and Interstitial Lung Disease (ILD) in England, Wales and Scotland Using Clinical Practice Research Datalink (CPRD), Secure Anonymised Information Linkage (SAIL) Databank and DataLoch. Clin Epidemiol. 2024;16:235-247

https://doi.org/10.2147/CLEP.S437937

2024

Alsallakh, M., Adeloye, D., Vasileiou, E., Sivakumaran, S., Akbari, A., Lyons, R. A., Robertson, C., Rudan, I., Davies, G. A., & Sheikh, A. (2024). Impact of the COVID-19 Pandemic on Influenza Hospital Admissions and Deaths in Wales: Descriptive National Time Series Analysis. JMIR public health and surveillance, 10, e43173. https://doi.org/10.2196/43173

Orton, C., Edwards, L., Seymour, D., Jones, M., Quinlan, P., Thompson, S., Goble, C., Quint, J., & Sheikh, A. (2024). Data as infrastructure: Systematic data curation addressing fundamental data content differences across the UK. International Journal of Population Data Science, 9(5). https://doi.org/10.23889/ijpds.v9i5.2683

Whittaker H, Adamson A, Stone P, Olubori P, Calvert J, Dodd J, et al. Sex differences in asthma and COPD hospital admission, readmission and mortality. BMJ Open Respiratory Research. 2025;12:e002808. https://doi.org/10.1136/bmjresp-2024-002808 

2025

Shackleford, A., Heaney, L. G., McDowell, P. J., Davies, G. A., Butler, C., Sweeney, J., & Busby, J. (2025). Investigating the Association Between Biologic Initiation and Medication Adherence in Severe Asthma: An Analysis of Linked Data. The journal of allergy and clinical immunology. In practice, S2213-2198(25)00610-5. Advance online publication. https://doi.org/10.1016/j.jaip.2025.06.029

Moore E, Al Sallakh M, Olajide O, Trusinska D, Jackson T, Shi T, Brown SJ, Robson JC, Ndosi M, Jani M, Sheikh SA, Kallis C, Lax SJ, Quint JK. Mapping Use of High Dose or Long-Term Oral Glucocorticoids and Steroid-Sparing Strategies in Adults With Chronic Conditions: A Rapid Scoping Review of Reviews. Pharmacoepidemiol Drug Saf. 2025 Oct;34(10):e70233. doi: 10.1002/pds.70233. PMID: 41088867; PMCID: PMC12521885. 

Gassasse Z, Khan ID, Mok E, Asick AM, Tan A, Sheikh A, Sinha I, Davies GA, Whittaker H, Kallis C, Quint JK. Association between income, employment status, and asthma outcomes: a systematic review and meta-analysis. Lancet Reg Health Eur. 2025 Jun 26;56:101367. doi: 10.1016/j.lanepe.2025.101367. PMID: 40688041; PMCID: PMC12268008.

Shackleford, A., Heaney, L. G., Redmond, C., McDowell, P. J., & Busby, J. (2025). Clinical remission attainment, definitions, and correlates among patients with severe asthma treated with biologics: a systematic review and meta-analysis. The Lancet. Respiratory medicine, 13(1), 23–34. https://doi.org/10.1016/S2213-2600(24)00293-5

Trusinska, D., Lee, B., Ferdous, S., Kwok, H. H. Y., Gordon, B., Gao, J., Ma, L., Xiong, H., Sheikh, S. A., Schwarze, J., Busby, J., Gibbons, C., Drysdale, S. B., Ritchie, S. L., Williams, T., & Shi, T. (2025). Real-world uptake of nirsevimab, RSV maternal vaccine, and RSV vaccines for older adults: a systematic review and meta-analysis. EClinicalMedicine, 84, 103281. https://doi.org/10.1016/j.eclinm.2025.103281

Lee, B., Trusinska, D., Ferdous, S., Pei, R., Kwok, H. H. Y., Schwarze, J., Williams, T. C., Gibbons, C., Quint, J. K., Sheikh, A., Drysdale, S. B., & Shi, T. (2025). Real-world effectiveness and safety of nirsevimab, RSV maternal vaccine and RSV vaccines for older adults: a living systematic review and meta-analysis. Thorax, 80(11), 838–848. https://doi.org/10.1136/thorax-2025-223376 

Whittaker, H., Kramer Fiala Machado, A., Hatam, S., Cook, S., Scully, S., Evans, H. T. T., Bolton, T., Kallis, C., Busby, J., Heaney, L. G., Sheikh, A., Quint, J. K., & CVD-COVID-UK/COVID-IMPACT Consortium (2025). Incidence and prevalence of asthma, chronic obstructive pulmonary disease and interstitial lung disease between 2004 and 2023: harmonised analyses of longitudinal cohorts across England, Wales, South-East Scotland and Northern Ireland. Thorax, 80(7), 466–477. https://doi.org/10.1136/thorax-2024-222699

Tibble, H., Alyami, R. A., Bush, A., Cunningham, S., Julious, S., Price, D., Quint, J. K., Turner, S., Wang, K., Wilson, A., Davies, G. A., Mukherjee, M., Chan, A. H. Y., Varghese, D., Jackson, T., Morgan, N., Daines, L., & Pinnock, H. (2025). Using routine primary care data in research: (in)efficient case studies and perspectives from the Asthma UK Centre for Applied Research. BMJ health & care informatics, 32(1), e101134. https://doi.org/10.1136/bmjhci-2024-101134

Busby, J., Khezrian, M., Patel, S., Tran, T. N., Rhodes, K., & Heaney, L. G. (2025). Exploring the carbon footprint of severe asthma and change after biologic therapy initiation: an analysis of Northern Irish data. ERJ open research, 11(3), 01009-2024. https://doi.org/10.1183/23120541.01009-2024 

Tibble, H., Sheikh, A. & Tsanas, A. Development and validation of a machine learning risk prediction model for asthma attacks in adults in primary care. npj Prim. Care Respir. Med. 35, 24 (2025). https://doi.org/10.1038/s41533-025-00428-8 

Thomas A, Nabwera H, Hawcutt DB, et al. Guide to understanding observational studies that use real-world data. Archives of Disease in Childhood. Published Online First: 06 November 2025. doi:10.1136/archdischild-2025-329491 https://adc.bmj.com/content/early/2025/11/06/archdischild-2025-329491 

Whittaker, H. R., Jani, M., Pearce, F. A., Bell, S., Kallis, C., Hawcutt, D., Brown, S., Neves, A. L., Robson, J., Shi, T., Lax, S. J., Sheikh, A., & Quint, J. K. (2025). Prescriptions of corticosteroids in primary care and related clinical indications: A national population-based cohort study in England. The Lancet Primary Care, 1(6), 100080. https://doi.org/10.1016/j.lanprc.2025.100080

Burden C, Gassasse Z, Alsallakh M, Quint JK, Fry R, Davies G. Impact of air pollution and asthma on school attendance and educational attainment: a scoping review. BMJ Open Respiratory Research. 2025;12:e003527. https://doi.org/10.1136/bmjresp-2025-003527 

2026

Schnier, Christian and McDowell, P. Jane and Busby, John and PDF, See, Prevalence and Healthcare Utilisation of Eosinophilic Chronic Obstructive Pulmonary Disease in the UK: An Observational Electronic Health Record-Based Cohort Study. Available at SSRN: https://ssrn.com/abstract=5961899 or http://dx.doi.org/10.2139/ssrn.5961899 

Schnier C, Busby J, Sheikh A, Quint JK, Price DB, Heaney LG. Validity of Using Prescription Medications to Classify Disease – A Retrospective Observational Study Using Routinely Collected Electronic Health Records from the UK. Pragmat Obs Res. 2026; 17: 1-14. https://doi.org/10.2147/POR.S553011 

Lee AR, Schofield PG, Olajide O, Osuolale O, Camacho E, McAndrew D, Buchan I, Barr B, Hawcutt DB, Sinha IP. Evaluating the impact of a parent champion model on bronchiolitis hospitalisation rates: a difference in differences study. Arch Dis Child. 2026 Jan 19;111(2):173-179. doi: 10.1136/archdischild-2025-328671. PMID: 41130663; PMCID: PMC12911602. 

Coyle, L. M., Schnier, C., McDowell, P. J., Redmond, C., Butler, C. A., & Heaney, L. G. (2026). Persistent long-term hypothalamic-pituitary-adrenal-axis suppression after maintenance oral corticosteroid withdrawal in severe asthma: Biochemical assessment is essential. The Journal of Allergy and Clinical Immunology: In Practice, 14(5), 1113–1120.e1. https://doi.org/10.1016/j.jaip.2026.02.013 

Coyle, Liam & Busby, John & McDowell, Jane & Price, David & Redmond, Charlene & Davies, Gwyneth & Quint, Jennifer & Heaney, Liam. (2026). Early Identification of 'High-Risk' Asthma and Progression to Bio-Eligibility: A Retrospective Cohort Study Using UK Data. 10.2139/ssrn.6172595. 

Trusinska D, Lee B, Ferdous S, Lansbury L, Burden C, Anand A, Stowe J, Mensah A, Lim W, Marsh K, Gibbons C, Shi T. Real-world evidence on RSV vaccine uptake, effectiveness, and safety in older adults: a systematic review and meta-analysis. Lancet Reg Health Eur. 2026 Feb 20;64:101623. doi: 10.1016/j.lanepe.2026.101623. PMID: 41767892; PMCID: PMC12936786.