CPHS seminar: Factorial Mendelian randomization

Speaker              

Jess Rees, Statistician, Edinburgh Clinical Trials Unit

Title                     

Factorial Mendelian randomization: using genetic variants to assess interactions

Abstract

Jess Rees will describe her work on extending Mendelian randomization to the factorial setting.  She will outline two distinct contexts for factorial Mendelian randomization: investigating interactions between risk factors, and investigating interactions between pharmacological interventions on risk factors. She will illustrate the methods using data from UK Biobank to investigate the interaction between body mass index and alcohol consumption on systolic blood pressure. 

Bio

Jess Rees joined the University of Edinburgh in February 2019 as a statistician at the Edinburgh Clinical Trials Unit.  She submitted her PhD in robust method development in Mendelian randomization at the University of Cambridge at the beginning of 2019.  Her work has mainly focused on developing methodology in Mendelian randomization when the instrumental variable assumptions are violated. 

Please register via Eventbrite.