Publications 2023 to Date

2023

[ASPIRED] Multicentre open label randomised controlled trial of immediate enhanced ambulatory ECG monitoring versus standard monitoring in acute unexplained syncope patients: the ASPIRED study. Matthew J Reed, Neil Grubb, Chris Lang, Steve Goodacre, Rachel O’Brien, Christopher J Weir, Praveen Thokala, Nicola Freeman, Caroline Blackstock, Lynn Dinsmore, Julia Boyd, Imad Adamestam, Pam Macrae, Robert Hannigan, Trudie Lobban. BMJ Open: Reed MJ, et al. BMJ Open Feb 2023;13:e069530. doi:10.1136/bmjopen-2022-069530

[CARE] Loan JMJ, Bacon A, van Beijnum J, Bhatt P, Bjornson A, Broomes N, Bullen A, Bulters D, Cahill J, Chavredakis E, Colombo F, Danciut M, Digpal R, Edwards RJ, Ferguson L, Forsyth L, Fouyas I, Ganesan V, Grover P, Gurusinghe N, Hall PS, Harkness K, Harris LS, Hayton T, Helmy A, Holsgrove D, Hutchinson PJ, Israni A, Kinsella E, Lewis S, Majeed S, Mallucci C, Mukerji N, Nair R, Neilson AR, Papadopoulos MC, Radatz M, Rossdeutsch A, Raza-Knight S, Stephen J, Stoddart A, Teo M, Turner C, Wade J, Walsh D, White D, White P, Wildman J, Wroe Wright O, Uff C, Ushewokunze S, Vindlacheruvu R, Kitchen N, Al-Shahi Salman R. Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma – protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot trial. BMJ Open Aug 2023, 13 (8) e075187; DOI: 10.1136/bmjopen-2023-075187

[COBIN] The importance of long-term follow-up in clinical trials. Norrie J.  Lancet Glob Health. 2023 Jul;11(7):e995-e996. doi: 10.1016/S2214-109X(23)00244-9.  PMID: 37349045 No abstract available.

[ESPRIT2] Effectiveness of laparoscopic removal of isolated superficial peritoneal endometriosis for the management of chronic pelvic pain in women (ESPriT2): protocol for a multi-centre randomised controlled trial.  Mackenzie SC, Stephen J, Williams L, Daniels J, Norrie J, Becker CM, Byrne D, Cheong Y, Clark TJ, Cooper KG, Cox E, Doust AM, Fernandez P, Hawe J, Holland T, Hummelshoj L, Jackson LJ, King K, Maheshwari A, Martin DC, Sutherland L, Thornton J, Vincent K, Vyas S, Horne AW, Whitaker LHR.  Trials. 2023 Jun 22;24(1):425. doi: 10.1186/s13063-023-07386-x.  PMID: 37349849 Free PMC article.

Definitions, acceptability, limitations, and guidance in the use and reporting of surrogate endpoints in trials: A scoping review.  Manyara AM, Davies P, Stewart D, Weir CJ, Young AE, Wells V, Blazeby J, Butcher NJ, Bujkiewicz S, Chan AW, Collins GS, Dawoud D, Offringa M, Ouwens M, Ross JS, Taylor RS, Ciani O.  J Clin Epidemiol. 2023 Jun 26:S0895-4356(23)00160-9. doi: 10.1016/j.jclinepi.2023.06.013. Online ahead of print.  PMID: 37380118 Review.

[DEFINE] Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study.  Solovyeva O, Dimairo M, Weir CJ, Hee SW, Espinasse A, Ursino M, Patel D, Kightley A, Hughes S, Jaki T, Mander A, Evans TRJ, Lee S, Hopewell S, Rantell KR, Chan AW, Bedding A, Stephens R, Richards D, Roberts L, Kirkpatrick J, de Bono J, Yap C.  BMC Med. 2023 Jul 5;21(1):246. doi: 10.1186/s12916-023-02937-0.  PMID: 37408015 Free PMC article. Review.

[PIONEER] Interventions for Perceptual Disorders in Stroke: A Systematic Review  Hazelton, C., Thomson, K., Todhunter-Brown, A., Campbell, P., Chung, C. S. Y., Dorris, L., Gillespie, D. C., Hunter, S. M., Mcgill, K., Nicolson, D. J., Williams, L. J. & Brady, M. C., 6 Apr 2023, In: Stroke.

[PREFFIR] Moss A, Daghem M, Tzolos E, Meah MN, Wang K-L, Bularga A, Adamson PD, Kwiecinski J, Fletcher A, Dawson D, Arumugam P, Sabharwal N, Greenwood JP, Townend J, Calvert PA, Rudd JHF, Berman D, Verjans J, Slomka P, Dey D, Forsyth L, Murdoch L, Lee RJ, Lewis S, Mills NL, van Beek EJR, Williams MC, Dweck MR, Newby DE on behalf of the PRE18FFIR Investigators. Coronary Atherosclerotic Plaque Activity and Future Coronary Events. JAMA Cardiol. Published online June 28, 2023. doi:10.1001/jamacardio.2023.1729

[PREPARE] In-hospital mortality risk stratification in children aged under 5 years with pneumonia with or without pulse oximetry: A secondary analysis of the Pneumonia REsearch Partnership to Assess WHO REcommendations (PREPARE) dataset.  Pneumonia REsearch Partnership to Assess WHO REcommendations (PREPARE) study group, Hooli, S., King, C., McCollum, E. D., Colbourn, T., Lufesi, N., Mwansambo, C., Gregory, C. J., Thamthitiwat, S., Cutland, C., Madhi, S. A., Nunes, M. C., Gessner, B. D., Hazir, T., Mathew, J. L., Addo-Yobo, E., Chisaka, N., Hassan, M., Hibberd, P. L., Jeena, P., & 53 others, 1 Apr 2023, In: International Journal of Infectious Diseases. 129, p. 240-250 11 p.

[PRIME2] Kunkler IH, Williams LJ, Jack WJL, Cameron DA, Dixon JM. Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer. NEJM 2023; 388: 585-594. DOI 10.1056/NEJMoa2207586