UKCRC Studies

Rheumatology / Orthopaedic:

DENS  ^{(duration of external neck stabilisation)}

MOTION  ^{(osteoarthritis)}

LASER ^{(assisted Staphylococcal eradication)}

OPPORTUNITY ^{(osteoarthritis in knees)}

SLEx ^(lupus)

TOPaZ ^{(Osteogenesis Imperfecta)}

TRIO-Physio ^{(physiotherapy vs knee replacement)}

ZiPP ^{(Paget's disease)}

Perioperative Medicine:

RESULT-HIP ^{(effect of haemoglobin transfusion threshold after hip fracture surgery on cardiac injury and death)}

Health Economics:

Neurology:

4AT ^{(triage tool for delirium)}

AGS-RTI ^{(reverse transcriptase inhibitors + interferon signalling)}

CARE ^{(symptomatic brain cavernoma)}

MS-SMART ^{(multiple sclerosis)}

RESTART ^{(spontaneous intracerebral haemorrhage)}

MND-SMART ^{(Motor Neurone Disease Systematic Multi-Arm Adaptive Randomised Trial)}

Neurosurgery:

Cardiology:

Cardiac CARE ^{(high-sensitivity cardiac troponin I)}

DIAMOND ^{(coronary atherosclerosis and PET CT)}

DUAL ACS  ^{(acute coronary syndrome)}

EVoLVeD ^{(early valve replacement)}

HighSTEACS ^{(high sensitivity Troponin)}

HiSTORIC ^{(high sensitivity Troponin)}

PRE¹⁸FFIR ^{(PET CT and myocardial infarction)}

SALTIRE II ^{(aortic stenosis)}

SCOT-HEART 2 ^{(computer tomography coronary angiography for the prevention of myocardial infarction)}

TARGET-CTCA ^{(using troponin to guide CTCA)}

Gastro-Intestinal:

GEM ^{(Crohn's disease)}

MARVEL ^{(ulcerative colitis)}

SPARE ^{(Crohn's disease)}

Mini MARVEL ^{(ulcerative colitis)}

MUSIC  ^{(ulcerative colitis and crohn's disease)}

Clinical Toxicology:

MAIL  ^{(macrophage therapy for acute liver injury)}

Emergency/Critical Care:

A2B ^{(alpha 2 agonists sedation agents)}

ASPIRED ^{(enhanced ambulatory ECG monitoring)}

HiSNAP ^{(paracetamol overdose)}

The RUFUS Study ^{(repurposing flumazenil for intramuscular treatment of coma due to         unintentional drug overdose - a dose-finding safety and efficacy phase II/III study)}

Respiratory:

PIB CAP ^{(personalised antibiotic treatment for pneumonia)} 

MucAct  ^(COPD)

TEMPESTAS ^{(effect of inhaled steroids in severe COPD patients)} 

Transplant:

HOT2 ^{(renal transport - delayed graft function)}

Paediatric:

ELVIS Kids ^{(upper respiratory tract infection)}

Obstetrics/Gynaecology:

BRIDGE-IT  ^{(emergency contraception)}

CHOICE ^{(cervical ripening at home or in hospital)}

METAFOR ^{(gestational diabetes)}