Completed Studies

Rheumatology / Orthopaedics:

AbbVie M13-549 ^{(moderately to severely active rheumatoid arthritis)}

AbbVie M13-542 ^{(safety and efficacy of ABT-494)}

ACT- Move ^{(efficacy of switching to SC tocilizumab)}

AXLES1 ^{(x-linked hypophosphatemia)}

FAB ^{(alendronic acid and wrist fractures)}

FAST ^{(febuxostat safety in gout)}

LASER ^{(assisted staphylococcal eradication)}

MALDI-MS ^{(kidney injury biomarkers)}

OPPORTUNITY ^{(osteoarthritis in knees)}

PRISM-EZ  ^{(paget's disease)}

SCOT ^{(NSAID safety in OA)}

TANGO ^{(efficacy of subcutaneous tanezumab)}

TRIO-Physio ^{(physiotherapy vs knee replacement)}

ZiPP LTE ^{(paget's disease)}

ZiPP  ^{(paget's disease}

Paediatrics:

BIDS ^{(bronchiolitis)}

CHILD-EU ^{(lung disease)}

Health Economics:

Allocative Efficiency in End of Life Care ^{(achieving a more cost-effective mix of services within health and social care services to maximise the health of the UK)}

Eribulin Audit ^{(post-adoption surveillance audit of new medicines for metastatic breast cancer in the real world)}

Info-BC ^{(decision making in early and advanced breast cancer)}

SATURNE ^{(Scottish adjuvant therapy unified routine data natural experiment)}

CORECT-R   ^{(creating a UK colorectal cancer intelligence hub)}

Public Health:

COVID Community study ^{(management of COVID-19 through data-driven research)}

APPRAISE ^{(alcohol intervention for remand prisoners)}

Stand Up for Health ^{(sedentary behaviour in call centres)}

ELVIS COVID ^{(nasal washout and gargling for improvement in COVID-19 symptoms)}

Neurology:

4AT ^{(triage tool for delirium)}

AGS-RTI  ^{(reverse transcriptase inhibitors + interferon signalling)}

CARE ^{(symptomatic brain cavernoma)}

CLOTS ^(stroke)

DelApp ^{(validation studies to assess the diagnostic accuracy of a software application for detection and monitoring of attentional deficits in delirium)}

EuroHYP-1 ^(stroke)

FOCUS ^(stroke)

HEMOTION ^{(haemoglobin transfusion)}

IST-3 ^(stroke)

LACI-2 ^{(prevention of recurrent lacunar stroke)}

MASK  ^(stroke)

MS-SMART ^{(multiple sclerosis)}

PREVENT-SVD ^{(small vessel stroke)}

RESTART ^{(spontaneous intracerebral haemorrhage)}

SOCLE II  ^(stroke)

SoSTART ^{(anticoagulants and brain haemorrhage)}

POSITIF ^{(post stroke fatigue)}

Cardiology:

Cardiac CARE ^{(high-sensitivity cardiac troponin I)}

cTnI Monitoring ^{(cardiac damage in breast cancer)}

DIAMOND ^{(coronary atherosclerosis and PET CT)}

EMPIRE ^{(effect of elafin on myocardial injury)}

FLAME

HighSTEACS ^{(high sensitivity troponin)}

MA3RS ^{(abdominal aortic aneurysms)}

National Atrial Fibrilliation Pilot

EVoLVeD ^{(early valve replacement)}

HiSTORIC ^{(high sensitivity troponin)}

PRE¹⁸FFIR ^{(PET CT and myocardial infarction)}

SALTIRE II ^{(aortic stenosis)}

SCOTHEART ^{(computer tomography coronary angiography for the prevention of myocardial infarction)}

Gastro-intestinal:

MOBIDIC ^{(E Coli detection in Crohn's)}

PREdiCCt ^{(crohn's disease flare up)}

TOPPIC ^{(prevent recurrence of crohn's disease)}

GEM ^{(crohn's disease)}

SPARE ^{(crohn's disease)}

MUSIC  ^{(crohn's disease)}

Palliative Care:

TiBoP ^{(cancer induced bone pain)}

MINT ^{(chemotheraphy induced peripheral neuropathy)}

GI-ACP ^{(advance care planning in cancer)}

Transplant:

HOT2 ^{(renal transport - delayed graft function)}

Emergency/Critical Care:

A2B ^{(alpha 2 agonists sedation agents)}

ABC Sepsis ^{(adult sepsis)}

ABLE ^{(age of blood evaluation)}

BP Together ^{(Towards An Integrated Self-Monitoring SolutIoN for Stroke/TIA)}

DESIST

ExPRES Sepsis ^{(test to predict high risk patients)}

INFECT ^{(phenotyping immune cell dysfunction)}

POP ^{(paracetamol overdose)}

RECOVER

SNAP

RAPID CTCA ^{(acute coronary syndrome)}

Maternal Critical Care ^{(pregnancy critical care admission)}

Telehealth:

COPD

COPD Respiratory Monitoring

HITS: Hypertension

Respiratory:

Monocyte Depletion

PIB CAP ^{(personalised antibiotic treatment for pneumonia)} 

Obstetrics / Gynaecology:

AFFIRM ^{(awareness of decreased foetal movements)}

EMPOWaR ^{(efficacy of metformin)}

GAPP ^{(management of chronic pelvic pain)}

DEXFEM ^{(endometrial glucocorticoid deficiency)} 

PAPAGENO ^{(prevention of gestational diabetes and pre-eclampsia in obese pregnant women in resource poor settings)}

ESPriT1 ^{(managing chronic pelvic pain in women)}

CHOICE ^{(cervical ripening at home or in hospital)}

METAFOR ^{(gestational diabetes)}

Endocrine:

BALANCE ^{(diabetes: digital disease management)}

RESORP ^{(recovery from acute pancreatitis)}

Virology:

ELVIS ^{(nasal irrigation for common cold)}

Methodology:

PROMiSe