Hayley Holt

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The COVIDENCE UK Research Study has been developed in response to the outbreak of coronavirus disease (COVID-19). We are asking people aged 16 years or older, from all parts of the UK and from all walks of life, to sign up and fill in an online questionnaire with details about their lifestyle and health.

Participants will then be contacted every month to check if they have developed any symptoms of coronavirus disease, and to ask some follow-up questions about participants' more general health and social circumstances.

The data we collect will be analysed in order to:

• advance understanding of risk factors for coronavirus disease among UK adults
• find out how quickly people recover from coronavirus disease and whether there are any long-term complications of this illness
• evaluate the impact of coronavirus disease on the physical, mental and economic wellbeing of the UK population
• establish a platform for future research on coronavirus disease in the UK.

To date, we have over 18,900 participants across the UK and have been featured in BBC News, Daily Express, The Mirror, The Lancet, The BMJ and more. To find out more information please visit our website and YouTube page for updates on our progress:

Covidence UK website (external website) 

About me

I have previously completed my B.S. in Biology at Kansas State University in the USA, followed by an MSc in Reproductive and Developmental Biology at Imperial College London. I have an interest in applied research and translational medicine.

Publications

• Talaei, M., Faustini, S., Holt, H. et al. Determinants of pre-vaccination antibody responses to SARS-CoV-2: a population-based longitudinal study (COVIDENCE UK). BMC Med 20, 87 (2022). https://doi.org/10.1186/s12916-022-02286-4
• Ishiguro S, Uppalapati D, Goldsmith Z, Robertson D, Hodge J, Holt H, et al. (2017) Exopolysaccharides extracted from Parachlorella kessleri inhibit colon carcinoma growth in mice via stimulation of host antitumor immune responses. PLoS ONE 12(4): e0175064. doi: https://doi.org/10.1371/journal.pone.0175064 

• Hayley Holt, Mohammad Talaei, Matthew Greenig, Dominik Zenner, Jane Symons, Clare Relton, Katherine S Young, Molly R Davies, Katherine N Thompson, Jed Ashman, Sultan Saeed Rajpoot, Ahmed Ali Kayyale, Sarah El Rifai, Philippa J. Lloyd, David A. Jolliffe, Sarah Finer, Stamatina Ilidriomiti, Alec Miners, Nicholas S. Hopkinson, Bodrul Alam, Paul E Pfeffer, David McCoy, Gwyneth A Davies, Ronan A Lyons, Christopher J Griffiths, Frank Kee, Aziz Sheikh, Gerome Breen, Seif O Shaheen, Adrian R Martineau. Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)  medRxiv 2021.03.27.21254452; doi: https://doi.org/10.1101/2021.03.27.21254452

Research Activity

• British Thoracic Society Winter Meeting 2021 spoken presentation: Risk factors for symptom-defined COVID-19: a population-based longitudinal study (COVIDENCE UK)

COVIDENCE UK Research Project webpage

Read more about COVIDENCE UK on the Asthma UK Centre for Applied Research project page.

Covidence UK Research Project page