Listing of available projects for 25/26 entry Applications for all projects must be submitted via the University of Edinburgh's Degree Finder. Please include a CV with your application and ensure you submit the recruitment form. WITHOUT THE RECRUITMENT FORM YOUR APPLICATION WILL NOT BE CONSIDERED Document Precision Medicine Recruitment Form (878.42 KB / DOCX) University of Glasgow projects can be found here UNIVERSITY OF EDINBURGH PROJECTSPROJECT TITLESUPERVISORA Personalized Approach - Putting the Squeeze on MesotheliomaDr Carsten Hansen Causal AI to discover mechanisms and surrogate markers of retinal and brain disease from observational datasetsDr Ian MaccormickChronic Pain, analgesic prescribing, and cognitive declineDr Chloe Fawns-Ritchie Computer modelling of the retinal microvasculature: a move towards personalised management of kidney disease and brain health through improved understanding of vascular dysfunction and injuryDr Tom MacGillivrayDefining vascular-immune cell heterogeneity and and intercellular communication in human vascular disease and dementiaProf Karen Horsburgh Developing a novel catalytic uncaging drug delivery system to deliver a focal therapy for post-radiotherapy tissue regenerationDr Elaine Emmerson Developing Multimodal Biomarkers and Computational Models for Objective and Subjective Impairments in Altered Cognitive States Using fNIRS, EEG, and Eye-TrackingDr Benjamin Peters Development and validation of an AI decision-support tool to improve diagnosis and risk stratification of patients presenting in the Emergency DepartmentProf Nicholas L Mills Development of a precision medicine-based gene therapy to treat atheroscleroticdiseaseProf Andrew H. BakerDevelopment of pH-Sensitive Metal-Organic Framework (MOF) for Targeted Drug Delivery in Pancreatic Cancer TreatmentDr Peisan (Sharel) E Epigenetic profiling associated with environmental exposure stress for stratifying disease riskDr Sari Pennings Identifying the role(s) of GPR56 and GPR97 in difficult-to-treat acute myeloid leukaemia cells to find new treatments for the diseaseDr Samanta Mariani Improving the prediction and treatment of human genetic disease by exploring the proteome-level impacts of dominant-negative mutationsDr Georg Kustatscher Investigating the impact of malaria and tuberculosis co-infections on disease outcomes Dr Jason Mooney LOCATE (Leveraging Organoids and Computational Analysis for Tracer Evaluation in PET); next generation individualised Total Body PET scanningDr Catriona Wimberley Mathematical modeling of pancreatic islet behaviour for the improvement of islet transplants in Type 1 DiabetesDr Linus Schumacher Meta-analysis of genome wide functional screens to identify broad-spectrum antiviraland immuno-therapeutic targetsDr Richard Sloan Multi-modal single-cell analysis of human kidney tissue to identify novel anti-inflammatory therapies for kidney diseaseDr Bryan Conway Multi-system prediction of frailtyProf Michelle Luciano Perivascular spaces and their relationship with changes in cognition over timeDr Francesca Chappell Revealing vulnerabilities of the microtube network and inter-cellular communication in gliomas through mechanistic computational modellingDr Dirk Sieger Systematic evidence-based approach to identifying and tailoring inflammation modulating treatments for patients with intracerebral haemorrhageDr Neshika Samarasekera The role of common cis-regulatory variation in modifying the penetrance of Lynch Syndrome variantsProf Albert Tenesa Using synthetic biology and quantitative analysis to understand differences in tolerance to tumorogeneic mutationsProf Sally Lowell Winter respiratory risk prediction model in adultsDr Ting Shi iCASE PROJECTSMRC’s iCASE awards provide students with experience of collaborative research with a non academic partner, enabling the student to spend a period of time with the non-academic partner (usually no less than three months over the lifetime of the PhD).PROJECT TITLESUPERVISORDissecting Macrophage-Fibroblast Cell Circuits in Liver Fibrosis using Spatial OmicsProf Prakash RamachandranPrecision Medicine for Intraoperative Brain Cancer SurgeryProf Marc Vendrell This article was published on 2024-11-11