Bowel-Star-UK

Bowel Cancer Screening Stratified by Risk

Summary

Screening for bowel cancer using FIT (Faecal Immunochemical Test) has been successful in saving lives in the UK – but it could save more lives by making better use of the test.

There are moves towards ‘risk-based screening’; this can increase the identification through screening of those who are most likely to be at high risk of bowel cancer. So instead of the FIT producing a ‘yes-no’ answer, the study will use its whole range of values in deciding what further tests (if any) are needed.

The study will examine other factors risk factors and see how they might lead to further improvements in screening performance and patient outcomes. The acceptability of these approaches to the UK general public will be explored. The impact on the running of the

NHS screening programmes will be measured – how much these alternative approaches might cost, and impact on health inequalities.

Key People

Name	Role	Institution
David Weller	Chief Investigator (Lead)	University of Edinburgh
Peter Sasieni	Co-Investigator (Co-Lead)	Queen Mary University of London
Christine Campbell	Co-Investigator	University of Edinburgh
Malcolm Dunlop	Co-Investigator	University of Edinburgh
Richard Houlston	Co-Investigator	University of Edinburgh
Stephen Duffy	Co-Investigator	Queen Mary University of London
Rhian Gabe	Co-Investigator	Queen Mary University of London
Sophie Whyte	Co-Investigator	University of Sheffield
Chrisitan von Wagner	Co-Investigator	University College London
Joanne Cairns	Co-Investigator	University of Hull
Sally Benton	Co-Investigator	Royal Surrey County Hospital NHS Foundation Trust
Peter Hall	Co-Investigator	University of Edinburgh
Robert Logan	Co-Investigator	Kings College Hospital NHS Foundation Trust
Farhat Din	Co-Investigator	University of Edinburgh
Robert Steele	Co-Investigator
Angela Niven	Project Manager	University of Edinburgh
Maheva Vallet	Data Manager	University of Edinburgh
Dharmishta Parmar	Senior Data Manager	Queen Mary University of London
Joy Li	Statistician	Queen Mary University of London
Hannah Miles	Qualitative Researcher	University of Hull
Chloe Thomas	Research Fellow	University of Sheffield
Yuxiao Sun	Research Assistant	University of Sheffield
Jazzine Smith	Research Fellow	University College London
Saskia Sanderson	Collaborator	University College London
Juliet Usher Smith	Professor of General Practice	University of Cambridge
Becky Dennison	Research Associate	University of Cambridge
Lily Taylor	Research Assistant	University of Cambridge
James Kang	PhD Student	University of Cambridge
Judith Strachan	Consultant Clinical Scientist	Scottish Bowel Screening Centre
Stephen Rowley	PPI Lead/Co-Applicant